The impact of two-component sensorial network in staphylococcal speciation
Related Experiment Video
Updated: Dec 25, 2025

A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues
Published on: February 19, 2019
Beatriz Rapun-Araiz1, Andreas F Haag2, Cristina Solano1
1Laboratory of Microbial Pathogenesis, Navarrabiomed, Complejo Hospitalario de Navarra (CHN)-Universidad Pública de Navarra (UPNA), IDISNA, Pamplona, 31008, Spain.
Abstract:
Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. Differences in the content of two-component systems are related with the capacity of the bacteria to colonize different niches or improve the efficiency to grow under the conditions of the existing niche. This review highlights differences in the TCS content between Staphylococcus aureus and Staphylococcus saprophyticus as a case study to exemplify how the ability to sense and respond to the environment is relevant for bacterial capacity to colonize and survive in/on different body surfaces.
Related Concept Videos
Speciation Rates
Genetics of Speciation
Global Regulatory Systems
Formation of Species
Gene Regulation in Microbial Communities: Quorum Sensing
Bacterial Signaling

