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Additive Manufacturing Technologies for Drug Delivery Applications.

Abdullah Mohammed¹, Amr Elshaer², Pooya Sareh¹

¹School of Engineering, University of Liverpool, Liverpool, L69 7ZX, UK.

International Journal of Pharmaceutics

|March 24, 2020

Summary

Personalized drug delivery systems are crucial due to patient variability. Additive manufacturing (AM) offers custom solutions for controlled-release medications, paving the way for a promising future in pharmaceuticals.

Keywords:

additive manufacturing drug delivery personalised mediations polypill

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Area of Science:

Pharmaceutical Sciences
Materials Science
Biotechnology

Background:

Patient variability in drug response necessitates personalized medicine.
Existing drug delivery systems struggle to address individual pharmacokinetic and demographic differences.
Novel manufacturing approaches are required for tailored therapeutic solutions.

Purpose of the Study:

To provide a comprehensive overview of additive manufacturing (AM) technologies for drug delivery.
To explore the application of AM in creating personalized dosages with controlled release profiles.
To investigate the potential, industrial scalability, and challenges of AM in pharmaceutical applications.

Main Methods:

Review of current additive manufacturing technologies (e.g., 3D printing).
Analysis of processed materials suitable for pharmaceutical applications.
Examination of existing research and industrial progress in AM-based drug delivery.

Main Results:

Additive manufacturing enables high customization and design freedom for drug delivery devices.
AM technologies facilitate the production of personalized medications with precise controlled-release characteristics.
Significant academic and industrial interest in AM for drug delivery is demonstrated by impressive product development.

Conclusions:

Additive manufacturing presents a transformative approach to personalized drug delivery.
AM offers significant potential for industrial-scale production of tailored pharmaceutical products.
Further investigation into AM technologies promises advancements in future healthcare solutions.