Relationship Between Serum Vitamin D Level and Ectopic Pregnancy: A Case-Control Study

Area of Science:

• Reproductive Endocrinology
• Nutritional Science

Background:

• Ectopic pregnancy is a significant cause of maternal morbidity.
• Vitamin D plays a crucial role in various physiological processes, including reproductive health.

Purpose of the Study:

• To investigate the association between serum vitamin D levels and ectopic pregnancy.
• To compare vitamin D status in women with ectopic pregnancy versus those with normal pregnancies.

Main Methods:

• A case-control study involving 150 women with ectopic pregnancy and 150 women with normal pregnancies.
• Serum vitamin D levels were measured and compared between the two groups.
• Statistical significance was determined using a p-value less than 0.05.

Main Results:

• No statistically significant difference in mean age was observed between the ectopic pregnancy group and the control group (p = 0.43).
• Serum vitamin D levels were significantly lower in women with ectopic pregnancy compared to the control group (p = 0.002).
• A high prevalence of vitamin D deficiency (60.66%) and insufficiency (21.33%) was noted in the study population.

Conclusions:

• Serum vitamin D levels are significantly lower in women experiencing ectopic pregnancy.
• These findings suggest a potential role for vitamin D in the pathophysiology of ectopic pregnancy.