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Liver metastasis from a non-recurrent atypical cranial meningioma: a case report
Francesco Limarzi1, Leonardo Solaini2, Giorgio Ercolani1,2
1University of Bologna.
Abstract:
Extracranial metastases from atypical meningioma are rare, and even more so in the liver. We report a case of a 68-years-old patient with atypical meningioma, treated with partial surgical resection in 2012, and gamma knife radiotherapy in 2014 in another hospital, exhibiting a liver metastasis 6 years after the initial surgical resection.
Insights
A rare case of atypical meningioma metastasizing to the liver is presented. This liver metastasis was detected six years after the initial surgical resection and gamma knife radiotherapy.
Area of Science:
- Neuro-oncology
- Hepatobiliary oncology
Background:
- Atypical meningioma is a rare brain tumor with a higher recurrence and metastasis risk than typical meningioma.
- Extracranial metastasis from meningioma is uncommon, with liver involvement being exceptionally rare.
Observation:
- A 68-year-old patient with a history of atypical meningioma, treated with partial surgical resection and gamma knife radiotherapy.
- The patient presented with a liver metastasis discovered six years post-initial surgical treatment.
Findings:
- This case highlights an unusual presentation of atypical meningioma with hepatic metastasis.
- The latency period of six years between initial treatment and metastasis detection is noteworthy.
Implications:
- This case underscores the importance of long-term surveillance for patients with atypical meningioma, even after successful primary treatment.
- Further research into the mechanisms and risk factors for extracranial metastasis in atypical meningioma is warranted.

