Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary lymphatics in SIDS--a comparative morphometric study.

S Ogbuihi1, P Zink

  • 1Gerichtlich-medizinisches Institut, Universität Bern, Switzerland.

Forensic Science International
|November 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of cultural traits and fungicidal activity of strains belonging to the fungal genus Chaetomium.

Journal of applied microbiology·2020
Same author

Traumatic venous aneurysm of the popliteal vein with outcome: a case report and review of the literature.

Journal of forensic sciences·2001
Same author

The organized subdural blood clot in forensic case work - a case report.

Forensic science international·2000
Same author

Nitric acid trihydrate (NAT) in polar stratospheric clouds.

Science (New York, N.Y.)·2000
Same author

[Crime scene and criminal findings site of an unknown cadaver in the field: reconstruction based on traces and clinical findings].

Archiv fur Kriminologie·1997
Same author

Identification of an unknown corpse by means of computed tomography (CT) of the lumbar spine.

Journal of forensic sciences·1995
Same journal

Technical note: Development of a UHPLC-MS/MS method for the analysis of hCG and IGF-I from dried blood spots: A preliminary study.

Forensic science international·2026
Same journal

A novel and robust deep learning model for sibling firearm matching.

Forensic science international·2026
Same journal

Changes in C-reactive protein levels over time in high-temperature environments using postmortem blood.

Forensic science international·2026
Same journal

Insights from the first synthetic cannabinoid clandestine lab dismantled in Brazil.

Forensic science international·2026
Same journal

Determination of the new psychoactive substances MDMB-4en-PINACA, ADB-BUTINACA and some of their metabolites in blood and urine using DLLE-LC-MS/MS: application to real forensic case samples.

Forensic science international·2026
Same journal

The revolver halo as a forensic marker: Raman spectroscopic evidence of primer-driven gunshot residue deposition.

Forensic science international·2026
See all related articles

Sudden Infant Death Syndrome (SIDS) cases show significantly more distended pulmonary lymphatics than controls. This suggests lymphatic stasis may be a contributing factor in SIDS, potentially impacting lung tissue.

Area of Science:

  • Pulmonary Pathology
  • Pediatric Autopsy
  • Lymphatic Physiology

Background:

  • Sudden Infant Death Syndrome (SIDS) remains a significant cause of infant mortality with unclear etiology.
  • Pulmonary findings in SIDS cases often include signs of asphyxia, complicating differential diagnosis with mechanical asphyxia.
  • Impaired lymphatic drainage has been hypothesized but not definitively established as a factor in SIDS.

Purpose of the Study:

  • To investigate potential differences in pulmonary lymphatic morphology between SIDS cases and age-matched controls.
  • To explore the hypothesis of lymphatic stasis as a contributing mechanism in SIDS.
  • To assess the forensic implications of pulmonary lymphatic findings in SIDS.

Main Methods:

  • Planimetric measurement of surface areas of various pulmonary lymphatics (pleural, interstitial, peribronchial, periarterial, perivenous).

Related Experiment Videos

  • Comparison of lymphatic surface areas between a group of SIDS cases (10 cases) and a control group (11 controls).
  • Statistical analysis of measured data to determine significant differences between the groups.

    • Main Results:

    • Pulmonary lymphatics in the SIDS group were significantly more distended than in the control group.
    • Highly significant differences in the surface areas of measured lymphatics were observed between SIDS and control groups.
    • A total of 2142 lymphatics were measured (1255 in SIDS, 887 in controls).

    Conclusions:

    • The findings indicate a potential feature of SIDS: lymphatic stasis, possibly secondary to impaired lymphatic drainage.
    • This lymphatic stasis could lead to subtle fibrotic changes in the lung's connective tissue framework.
    • The results contribute to understanding SIDS pathophysiology and differentiating it from mechanical asphyxia.