Addressing a Diagnosis of Brain Death in Hypernatremia Situation

Hypernatremia and the state of plasma hypertonia are part of the alterations of insipid diabetes that are integrated to the brain death (BD) syndrome. Hypernatremia should be corrected as early as possible to make the clinical diagnosis of BD and to avoid its potential deleterious effect on the subsequent operation of the liver graft. Transcranial Doppler is a very valuable tool for the diagnosis of cerebral circulatory arrest associated with BD. The correction of natremia is made through the use of hypotonic solutions, and using of pyrogen-free distilled water intravenously in special cases, which controls the possibility of hemolysis in the donor. In our study, isolated severe hypernatremia corrected before ablation was not associated with liver graft failure in the recipient.