Related Experiment Video
Updated: Dec 25, 2025

09:24
A Rapidly Incremented Tethered-Swimming Maximal Protocol for Cardiorespiratory Assessment of Swimmers
Published on: January 28, 2020
9.3K
A "Step-Ramp-Step" Protocol to Identify the Maximal Metabolic Steady State
Danilo Iannetta1, Erin Calaine Inglis1, Silvia Pogliaghi2
1Faculty of Kinesiology, University of Calgary, Calgary, Alberta, CANADA.
Medicine and Science in Sports and Exercise
|March 25, 2020
Summary
The step-ramp-step (SRS) protocol accurately estimates the power output (PO) at the respiratory compensation point (RCP), which represents the maximal metabolic steady state in healthy individuals during cycling.
Area of Science:
- Exercise Physiology
- Sports Science
- Metabolic Testing
Background:
- The oxygen uptake (V̇O2) at the respiratory compensation point (RCP) is a key indicator of maximal metabolic steady state.
- Traditional ramp-incremental exercise protocols struggle to accurately determine the power output (PO) at RCP.
Purpose of the Study:
- To evaluate the effectiveness of a novel "step-ramp-step" (SRS) cycling protocol for estimating the PO at RCP.
- To validate the use of RCP as a surrogate for maximal metabolic steady state.
Main Methods:
- Healthy volunteers performed a "step-ramp-step" protocol involving moderate and heavy intensity steps with an intervening ramp test.
- Ventilatory and gas exchange data were analyzed to determine V̇O2 at lactate threshold (LT) and RCP.
- Power output at RCP was extrapolated using linear regression between LT and heavy intensity data.
Main Results:
- Participants completed 30-minute constant-power tests at the SRS-estimated RCP, achieving a steady-state V̇O2 comparable to ramp-identified RCP values.
- Exercise at 5% above the SRS-estimated RCP resulted in incomplete trials and non-steady-state responses in most participants.
- The SRS protocol demonstrated high within-participant consistency for V̇O2 at RCP.
Conclusions:
- The SRS protocol accurately predicts the power output associated with maximal metabolic steady state in healthy individuals.
- The respiratory compensation point (RCP) serves as a valid surrogate for maximal metabolic steady state during cycling.
- The SRS protocol offers a reliable method for determining critical exercise intensity thresholds.
Related Concept Videos
Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations
169
Gentamicin, an aminoglycoside antibiotic, is commonly administered via intermittent intravenous infusion to treat severe infections. An intermittent one-hour infusion of gentamicin, administered at eight-hour intervals, allows for precise control of plasma drug concentrations, minimizing toxicity while ensuring therapeutic efficacy. Pharmacokinetic principles govern the dynamics of plasma concentrations and can be mathematically described using specific equations.The plasma drug concentration...
169
Energy-requiring Steps of Glycolysis
170.9K
Glucose is the source of nearly all energy used by organisms. The first step of converting glucose into usable energy is called glycolysis. Glycolysis occurs in the cytosol of the cell over two phases: an energy-requiring phase and an energy-releasing phase. Over the first three steps, glucose is converted into different forms and attached to two phosphate groups donated by two ATP molecules, resulting in an unstable sugar. In the next two stages, the unstable sugar splits into two sugar...
170.9K

