Related Experiment Videos
Conformational modification of the PRP-hexapeptide by a direct covalent attachment of aromatic side chain groups
Z Szewczuk1, A Kubik, I Z Siemion
1Institute of Chemistry, University of Wroclaw, Poland.
International Journal of Peptide and Protein Research
|August 1, 1988
Abstract:
PRP-hexapeptide possessing the azo-bridge between Tyr1 and Phe5 residues, called azo-PRP-hexapeptide: (formula; see text), was synthesized and tested for immunoregulatory activity. High biological activity of the synthesized azo-PRP-hexapeptide suggests that the biologically active conformation of PRP-hexapeptide must be such that both aromatic rings (Tyr and Phe) are apparently close to each other.