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Updated: Dec 25, 2025

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
Published on: July 25, 2011
Imaging in oral cancers: A comprehensive review
Abhishek Mahajan1, Ankita Ahuja1, Nilesh Sable1
1Department of Radiodiagnosis and Imaging, Tata Memorial Hospital, Mumbai 400012, India.
This review simplifies imaging anatomy and methods for oral cavity squamous cell carcinoma (OSCC). It highlights key imaging findings crucial for diagnosing, staging, and managing OSCC, impacting patient prognosis and treatment.
Area of Science:
- Radiology
- Oncology
- Head and Neck Surgery
Background:
- Oral cavity squamous cell carcinoma (OSCC) requires accurate staging for effective treatment planning.
- The complex anatomy of the oral cavity necessitates specialized imaging expertise.
- Imaging is vital for locoregional staging, metastatic work-up, and post-treatment surveillance of OSCC.
Purpose of the Study:
- To simplify the relevant imaging anatomy of the oral cavity.
- To guide the selection of optimal imaging methods for OSCC.
- To highlight key imaging findings that influence OSCC prognosis and management.
Main Methods:
- Review of current imaging modalities used for OSCC.
- Correlation of anatomical structures with cancer spread patterns.
- Analysis of imaging findings predictive of prognosis and treatment response.
Main Results:
- Detailed explanation of oral cavity anatomy relevant to OSCC.
- Guidance on choosing appropriate imaging techniques (e.g., MRI, CT, PET-CT).
- Identification of critical imaging features for staging and treatment planning.
Conclusions:
- Accurate interpretation of imaging is essential for optimal OSCC management.
- Understanding anatomical spread facilitates precise disease extent determination.
- This review provides a framework for radiologists in evaluating OSCC.
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