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Updated: Dec 25, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Syndrome of inappropriate antidiuretic hormone associated with eosinophilic granulomatosis and polyangiitis
Michael S Lundin1,2, Beenu Kaw3, Rajit Pahwa4
1Internal Medicine, Michigan State University, East Lansing, Michigan, USA makala.lundin@gmail.com.
Abstract:
A 62-year-old man presented with classic signs and symptoms of eosinophilic granulomatosis and polyangiitis (EGPA, also known as Churg-Strauss syndrome)-mononeuritis multiplex, palpable purpura, hypereosinophilia, positive P-ANCA (perinuclear anti-neutrophil cytoplasmic antibodies) developed diffuse alveolar haemorrhage. The patient had longstanding mild hyponatraemia, but developed moderate and symptomatic hyponatraemia characteristic of the syndrome of inappropriate antidiuretic hormone. The patient's serum sodium returned to his baseline- mildly hyponatraemic, after initiation of treatment targeted towards EGPA.
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