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High FDG Uptake in Pleomorphic Hyalinizing Angiectatic Tumor.
Asako Yamamoto1, Yoshinao Kikuchi2, Satoshi Abe3
1From the Departments of Radiology.
Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare neoplasm. This case highlights significant FDG uptake in a low-grade PHAT, offering insights for imaging diagnosis.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare mesenchymal neoplasm.
- PHAT typically presents as a locally aggressive, low-grade tumor with uncertain lineage.
- These tumors commonly affect the lower extremities.
Observation:
- A 74-year-old woman presented with an enlarging mass in the right popliteal fossa.
- FDG PET/CT imaging was performed to assess the tumor's biological activity.
- The imaging revealed significant accumulation of FDG (SUVmax, 23.0) in the solid component of the mass.
Findings:
- Surgical resection and pathological examination confirmed the diagnosis of PHAT.
- The resected tumor exhibited a low-grade malignant nature.
- Notably, the PHAT demonstrated high FDG avidity, exceeding expectations for its grade.
Implications:
- This case suggests that significant FDG uptake can occur in low-grade PHAT.
- FDG PET/CT findings may aid in the characterization and diagnosis of PHAT.
- Understanding FDG avidity in PHAT is crucial for accurate staging and treatment planning.
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