Analysis of morpheaform basal cell carcinoma

Biopsies of morpheaform basal cell carcinomas (MBCCs) were separated into 2 groups based on histological features: 1) a pure morpheaform group with narrow elongated strands of basaloid cells in a dense fibrous stroma; and 2) a complex morpheaform group with pure morpheaform regions as well as regions with other histological patterns (nodular, etc.). Analysis by sex and body location revealed a female predominance in the pure morpheaform group. Lesions were found primarily on the mid-face in women with pure MBCCs. Using a monoclonal antibody which identifies eccrine duct in routinely fixed tissues, we could not identify eccrine ductal differentiation in MBCCs.