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Hand hygiene01:23

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Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
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Chlorhexidine Allergy: Current Challenges and Future Prospects.

Chirawat Chiewchalermsri1,2, Mongkhon Sompornrattanaphan3, Chamard Wongsa3

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Journal of Asthma and Allergy
|March 27, 2020
PubMed
Summary

Chlorhexidine allergy is rising, causing reactions from mild rashes to severe anaphylaxis. This review covers clinical signs, diagnosis, and management of chlorhexidine hypersensitivity.

Keywords:
allergyanaphylaxisantisepticschlorhexidinehypersensitivityperioperative

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Area of Science:

  • Medical Science
  • Allergology
  • Pharmacology

Background:

  • Chlorhexidine, a bisbiguanide antiseptic since 1954, is widely used in healthcare.
  • Increasing reports of chlorhexidine allergy, especially in procedural settings, are noted.
  • Hypersensitivity reactions range from cutaneous symptoms to life-threatening anaphylaxis.

Purpose of the Study:

  • To review current evidence on chlorhexidine allergy.
  • Focus on clinical manifestations, diagnostics, management, and prevention.
  • Highlight unique aspects of chlorhexidine hypersensitivity.

Main Methods:

  • Literature review of recent clinical evidence.
  • Synthesis of data on diagnosis and management strategies.
  • Emphasis on preventive measures for allergic patients.

Main Results:

  • Clinical presentations of chlorhexidine allergy vary widely.
  • Diagnostic methods include skin testing and drug provocation.
  • Management involves avoidance and prompt treatment of reactions.
  • Standardized labeling of chlorhexidine-containing products is lacking.

Conclusions:

  • Chlorhexidine allergy poses a significant clinical challenge.
  • Awareness of diverse reactions and routes of exposure is crucial.
  • Effective management and prevention strategies are essential for patient safety.