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Updated: Dec 25, 2025

A Bacterial Oral Feeding Assay with Antibiotic-Treated Mosquitoes
Published on: September 12, 2020
Use of Microbiota to Fight Mosquito-Borne Disease
Wei Huang1, Sibao Wang2, Marcelo Jacobs-Lorena1
1Department of Molecular Microbiology and Immunology, Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Abstract:
Mosquito-borne diseases cause more than 700 million people infected and one million people die (Caraballo and King, 2014). With the limitations of progress toward elimination imposed by insecticide- and drug-resistance, combined with the lack of vaccines, innovative strategies to fight mosquito-borne disease are urgently needed. In recent years, the use of mosquito microbiota has shown great potential for cutting down transmission of mosquito-borne pathogens. Here we review what is known about the mosquito microbiota and how this knowledge is being used to develop new ways to control mosquito-borne disease. We also discuss the challenges for the eventual release of genetically modified (GM) symbionts in the field.
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