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A Fine-Scale Genetic Map for Vervet Monkeys.

Susanne P Pfeifer¹

¹Center for Evolution and Medicine, School of Life Sciences, Arizona State University, Tempe, AZ.

Molecular Biology and Evolution

|March 27, 2020

Summary

Recombination rates in vervet monkeys show reduced broad-scale rates and a narrower genomic focus compared to great apes. Purifying and background selection appear to be key drivers of these patterns in vervet monkeys.

Area of Science:

Evolutionary biology
Genomics
Population genetics

Background:

The evolution of recombination rates is crucial for understanding genome evolution but remains poorly understood due to limited genomic resources across species.
Recombination rates have been studied in detail in humans and great apes, showing broad-scale conservation but fine-scale variation.

Purpose of the Study:

To construct the first fine-scale genetic map for vervet monkeys.
To compare recombination patterns in vervet monkeys with those of great apes to understand evolutionary processes shaping these rates across primates.

Main Methods:

Whole-genome population genetic data from ten vervet monkeys were analyzed.
Comparative analyses were performed between vervet monkeys and great apes.

Keywords:

African green monkey genetic map recombination vervet monkey

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Main Results:

Analyses suggest purifying and background selection play a dominant role in shaping variation patterns in vervet monkeys, indicated by correlations with diversity and divergence.
Vervet monkeys exhibit a generally reduced broad-scale recombination rate and a narrower genomic region for recombination events compared to great apes.

Conclusions:

The findings highlight significant differences in recombination rate patterns between vervet monkeys and great apes.
Further research is needed to identify genomic features and evolutionary processes driving recombination rate variation across primates.