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The NYU Children's Health and Environment Study
Leonardo Trasande1,2,3,4,5, Akhgar Ghassabian6,7,8, Linda G Kahn6
1Department of Pediatrics, New York University School of Medicine, New York, NY, USA. Leonardo.Trasande@nyumc.org.
European Journal of Epidemiology
|March 27, 2020
Summary
The NYU Children's Health and Environment Study (CHES) investigates prenatal chemical exposures on child development. This research pools data with the ECHO Program to examine environmental impacts on childhood health outcomes.
Area of Science:
- Environmental health
- Pediatric health
- Reproductive health
Background:
- Prenatal exposure to non-persistent chemicals poses potential risks to fetal and postnatal development.
- Understanding environmental influences on child health is crucial for early intervention and prevention strategies.
- The NYU Children's Health and Environment Study (CHES) was established to address these critical research gaps.
Purpose of the Study:
- To evaluate the impact of prenatal non-persistent chemical exposures on fetal and postnatal growth.
- To collaborate with the National Institutes of Health Environmental influences on Child Health Outcomes (ECHO) Program.
- To investigate the effects of the preconceptual, prenatal, and postnatal environment on childhood obesity, neurodevelopment, and other health outcomes.
Main Methods:
- Recruitment of pregnant women aged 18 years or older, less than 18 weeks pregnant, with low-risk pregnancies.
- Data collection through questionnaires and biological specimens during routine prenatal visits at <18, 18-25, and >25 weeks gestation.
- Continued data collection at birth and regular postpartum intervals, including biological specimen and questionnaire data.
Main Results:
- 2469 pregnant women were recruited between March 2016 and April 2019.
- 2000 live deliveries (2037 children) were included in the study.
- 1624 (80%) of the children's mothers consented to postnatal follow-up.
Conclusions:
- The NYU CHES study provides valuable data on the effects of environmental exposures during critical developmental periods.
- Collaboration with the ECHO Program enhances the scope and impact of the research findings.
- The study is well-positioned to contribute significant insights into the environmental determinants of child health.

