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Related Experiment Videos

Hypernatremia in calves.

J K Pringle1, L M Berthiaume

  • 1University of Guelph, Ontario, Canada.

Journal of Veterinary Internal Medicine
|April 1, 1988
PubMed
Summary
This summary is machine-generated.

Sodium chloride intoxication (hypernatremia) in calves can occur from electrolyte solution errors during diarrhea treatment. Even normal calves rapidly develop severe hypernatremia and clinical signs after consuming concentrated electrolyte solutions.

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Area of Science:

  • Veterinary Medicine
  • Animal Physiology
  • Toxicology

Background:

  • Neonatal diarrhea in calves is often treated with oral electrolyte solutions.
  • Errors in mixing these solutions can lead to electrolyte imbalances.

Observation:

  • Two diarrheic calves developed hypernatremia (serum sodium 171.6 and 208.0 mEq/l) due to presumed mixing errors.
  • Clinically normal calves experimentally given concentrated electrolyte solutions (approx. 2750 mEq sodium) willingly consumed them.
  • These experimental calves developed hypernatremia (serum sodium 176.0 and 179.8 mEq/l) within 6 hours.

Findings:

  • Hypernatremia in calves presents with depression, weakness, dehydration, and diarrhea.
  • Severe hypernatremia can lead to periodic convulsions and death.

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  • Cerebrospinal fluid electrolyte levels mirrored serum changes.

    • Implications:

    • Highlights the critical importance of accurate electrolyte solution preparation in calf therapy.
    • Underscores the rapid onset and potential lethality of hypernatremia in calves.
    • Suggests careful monitoring for electrolyte imbalances during treatment for neonatal calf diarrhea.