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Updated: Dec 25, 2025
Isolation and Flow Cytometric Characterization of Murine Small Intestinal Lymphocytes
Published on: May 8, 2016
[Infections of the small intestine]
1Department of Pathology, UZ Ghent, Ghent University, De Pintelaan 185, B9000 Ghent, (Belgium).
Insights
Small intestinal infections are common worldwide, causing significant child mortality from diarrheal disease. This review covers common causes, clinical and histological features, and classifies infections as acute or chronic for better diagnosis.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Pathology
Context:
- Small intestinal infections are a major global health concern, particularly impacting young children with high mortality rates from diarrheal disease.
- Pathogen diversity leads to varied pathological and epidemiological characteristics of these infections globally.
- Understanding these variations is crucial for effective disease management and prevention strategies.
Purpose:
- To review the most common causes of small intestinal infections.
- To describe the clinical and histological aspects of these infections.
- To classify small intestinal infections into acute and chronic forms to aid diagnosis.
Summary:
- This paper provides a comprehensive review of prevalent small intestinal pathogens.
- It details the clinical manifestations and histological findings associated with these infections.
- A classification system distinguishing acute from chronic infections based on inflammatory infiltrates is presented to assist in accurate diagnosis.
Impact:
- Facilitates accurate diagnosis of small intestinal infections by differentiating between acute and chronic presentations.
- Provides essential information for healthcare professionals managing diarrheal diseases, especially in pediatric populations.
- Contributes to a better understanding of the global epidemiology and pathology of small intestinal infections.
Abstract:
Small intestinal infections are, together with colonic infections, amongst the most frequent occurring diseases worldwide and they harass mankind. Especially among young children there are enormous numbers of deaths due to diarrhoeal disease. They can be caused by a great diversity of pathogens and their pathological and epidemiological features as well as their incidence can often differ in different areas of the world.In this paper the most common causes of small intestinal infections are reviewed and some characteristics of their clinical and histological aspects are described. Moreover, the different infectious diseases are classified into acute and chronic as the recognition of the type of inflammatory infiltrate may be help ful to make a correct diagnosis.
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