Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

459
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
459
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

484
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
484
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

194
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
194
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

337
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
337
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

320
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
320
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

763
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
763

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Race and Ethnicity Have a Significant Effect on the Disclosure of Erectile Function: An Analysis of NHANES Response Patterns.

Urology·2022
Same author

Exploring the relationship between socioeconomic status and erectile dysfunction: an analysis of the National Health and Nutrition Examination Survey.

International journal of impotence research·2022
Same author

Disorders of Ejaculation: An AUA/SMSNA Guideline.

The Journal of urology·2021
Same author

Presentation and resolution of gender dysphoria as a positive symptom in a young schizophrenic man who presented with self-emasculation: Frontiers of bioethics, psychiatry, and microsurgical genital reconstruction.

Clinical case reports·2020
Same author

Utility of dynamic MRA in the evaluation of male erectile dysfunction.

Abdominal radiology (New York)·2019
Same author

Effects of valganciclovir on spermatogenesis in renal transplant patients - results of a multicenter prospective nonrandomized study.

Transplant international : official journal of the European Society for Organ Transplantation·2019

Related Experiment Video

Updated: Dec 25, 2025

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
08:53

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

6.6K

Viral lower urinary tract infections.

Darius A Paduch1

  • 1Department of Urology, Weill Medical College of Cornell University, 525 East 68th Street, ST-924A, New York, NY 10021 USA.

Current Prostate Reports
|March 28, 2020
PubMed
Summary
This summary is machine-generated.

Viral lower urinary tract infections (UTIs) are increasingly recognized in immunocompromised patients. Early diagnosis using molecular techniques and treatment with cidofovir can prevent severe complications like hemorrhagic cystitis.

Keywords:
CystitisHerpes Simplex VirusHerpes Simplex Virus TypeRespiratory Syncytial VirusWest Nile Virus

More Related Videos

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice
10:23

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

Published on: December 1, 2017

17.8K
Expression of Transgenes in Native Bladder Urothelium Using Adenovirus-Mediated Transduction
06:01

Expression of Transgenes in Native Bladder Urothelium Using Adenovirus-Mediated Transduction

Published on: October 6, 2022

1.7K

Related Experiment Videos

Last Updated: Dec 25, 2025

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
08:53

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

6.6K
Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice
10:23

Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

Published on: December 1, 2017

17.8K
Expression of Transgenes in Native Bladder Urothelium Using Adenovirus-Mediated Transduction
06:01

Expression of Transgenes in Native Bladder Urothelium Using Adenovirus-Mediated Transduction

Published on: October 6, 2022

1.7K

Area of Science:

  • Virology
  • Infectious Diseases
  • Urology

Background:

  • Lower urinary tract infections (UTIs) are typically bacterial, but viral causes are emerging.
  • Viral UTIs, particularly hemorrhagic cystitis, are increasingly diagnosed in immunocompromised individuals post-transplant.
  • BK virus, adenovirus, and cytomegalovirus are key pathogens in post-transplant hemorrhagic cystitis.

Purpose of the Study:

  • To review the epidemiology of viral lower UTIs.
  • To discuss diagnostic challenges and current therapeutic strategies for viral UTIs.
  • To highlight the importance of early diagnosis and treatment in preventing morbidity.

Main Methods:

  • Literature review focusing on viral lower UTIs, diagnosis, and treatment.
  • Emphasis on molecular diagnostic techniques, especially real-time PCR for viral load quantification.
  • Discussion of antiviral agents, with a focus on cidofovir.

Main Results:

  • Viral UTIs are uncommon in immunocompetent hosts but significant in immunocompromised populations.
  • Real-time PCR is the preferred method for diagnosing viral UTIs and monitoring viral load.
  • Cidofovir demonstrates efficacy against common viral pathogens causing UTIs.

Conclusions:

  • Viral lower UTIs require specific diagnostic and management approaches, especially in transplant recipients.
  • Timely diagnosis and treatment are crucial to mitigate the severe morbidity associated with viral hemorrhagic cystitis.
  • Antiviral therapies, such as cidofovir, are essential for managing these infections.