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Related Concept Videos

Other Disorders of Digestive System01:30

Other Disorders of Digestive System

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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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What is Monogastric Digestion?01:50

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The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
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Major Organs of the Digestive System01:19

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The digestive system is responsible for the ingestion of food, secretion of enzymes, mixing and digesting food, absorption of the nutrients and defecation. The human digestive system consists of two major parts: the gastrointestinal tract and the accessory digestive organs.
Gastrointestinal tract:
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Regulation of the Digestive System01:25

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Digestive activity regulation hinges on three primary components. Activation is prompted by a multitude of mechanical and chemical indicators, primarily detected by receptors within the stomach and intestines' walls. These receptors predominantly respond to factors such as mechanical stretching of the organ walls, changes in pH and osmolarity, and the presence of digesting materials and their by-products.
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Factors Influencing Drug Absorption: Disease States and Pharmacology01:25

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Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
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Anatomy of the Gastrointestinal System01:26

Anatomy of the Gastrointestinal System

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The human digestive system is an intricate and essential network for nutrient absorption and waste elimination. It encompasses the gastrointestinal (GI) tract and several accessory organs.
Here's a detailed walkthrough of this complex system:
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Updated: Dec 25, 2025

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Covid-19 and the digestive system.

Sunny H Wong1,2, Rashid Ns Lui1,2, Joseph Jy Sung1,2

  • 1Institute of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong.

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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect the gastrointestinal tract, causing symptoms like diarrhea. This review covers the gastrointestinal aspects of the novel coronavirus disease pandemic.

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Area of Science:

  • Virology
  • Gastroenterology
  • Infectious Diseases

Background:

  • The COVID-19 pandemic is caused by SARS-CoV-2, a novel coronavirus.
  • While respiratory symptoms are common, gastrointestinal manifestations occur in some patients.
  • SARS-CoV-2 belongs to the Betacoronavirus genus, which includes SARS-CoV and MERS-CoV.

Purpose of the Study:

  • To review the significant gastrointestinal aspects of SARS-CoV-2 infection.
  • To highlight the implications of gastrointestinal involvement in disease management and transmission.

Main Methods:

  • Review of existing studies on SARS-CoV-2 and gastrointestinal symptoms.
  • Analysis of findings related to viral RNA detection in stool.
  • Examination of angiotensin-converting enzyme 2 (ACE2) expression in gastrointestinal cells.

Main Results:

  • SARS-CoV-2 RNA has been detected in the stool of infected individuals.
  • Angiotensin-converting enzyme 2, the viral receptor, is highly expressed in gastrointestinal epithelial cells.
  • Evidence suggests active SARS-CoV-2 infection and replication within the gastrointestinal tract.

Conclusions:

  • Gastrointestinal involvement is a notable feature of SARS-CoV-2 infection.
  • The presence of the virus in the GI tract has implications for disease control and patient management.
  • Further understanding of these gastrointestinal aspects is crucial for pandemic response.