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A device to evoke acetylcholine release electrically in the guinea pig myenteric plexus/longitudinal muscle
1Department of Pharmacology, School of Medicine, University of California, Los Angeles.
Methods and Findings in Experimental and Clinical Pharmacology
|November 1, 1988
Abstract:
A stimulator was developed to evoke acetylcholine release in the myenteric plexus-longitudinal muscle preparation from the guinea pig ileum. A power output stage was devised to allow a conventional stimulator to drive the low impedance presented by this type of preparation. To eliminate electrode polarization, the polarity of the stimulus is alternated. A peak reading ammeter is included which allows the investigator to monitor the stimulus.