[Biological Product Development Strategies for Prevention and Treatment of Coronavirus Disease 2019]

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Cai-Xia Yan1, Jia Li1, Xin Shen1

  • 1State Key Laboratory of Oral Diseases , National Clinical Research Center for Oral Diseases，West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition
|March 29, 2020
PubMed

Insights

Biological products offer promising strategies for preventing and treating coronavirus disease 2019 (COVID-19). This review explores the potential of therapies like interferon and vaccines against SARS-CoV-2.

Area of Science:

  • Virology
  • Immunology
  • Public Health

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global health emergency.
  • High transmissibility and mortality necessitate urgent, effective prevention and treatment strategies.
  • Previous outbreaks of SARS and MERS highlight the need for advanced medical countermeasures.

Purpose of the Study:

  • To review the potential applications of biological products in preventing and treating COVID-19.
  • To explore therapeutic avenues based on research from SARS and MERS.
  • To provide insights for future strategies against SARS-CoV-2.

Main Methods:

  • Literature review of existing research on biological products and coronaviruses.
  • Analysis of therapeutic approaches used for SARS and MERS.
  • Synthesis of findings on potential COVID-19 interventions.

Main Results:

  • Biological products, including interferon, convalescent plasma, and vaccines, show promise.
  • Therapeutic antibodies and intestinal micro-ecological regulators are also discussed.
  • Evidence from SARS and MERS informs potential COVID-19 treatments.

Conclusions:

  • Biological products represent a promising avenue for combating COVID-19.
  • Further research and development are crucial for effective prevention and treatment.
  • These strategies may aid in overcoming the COVID-19 pandemic.
Keywords:
Biological productsCOVID-19MERSSARSSARS-CoV-2

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