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Tracking the Development of Cerebrovascular Risk Factors Following Pregnancy With Preeclampsia
Madeline Lederer1, Adriana Wong2, Daniela Diego3
1University of Miami Miller School of Medicine, Miami, Florida.
Insights
Preeclampsia significantly increases the risk of developing cerebrovascular risk factors like hypertension and diabetes. Early management of these conditions is crucial to reduce long-term stroke risk in affected women.
Area of Science:
- Obstetrics and Gynecology
- Neurology
- Cardiology
Background:
- Preeclampsia is a serious pregnancy complication.
- Cerebrovascular risk factors pose a significant threat to long-term health.
- Understanding the post-preeclampsia trajectory of these risk factors is vital.
Purpose of the Study:
- To assess the incidence of cerebrovascular risk factors after preeclampsia.
- To evaluate the management of these risk factors in affected women.
- To identify disparities in risk factor development and treatment.
Main Methods:
- Retrospective chart review of women with preeclampsia (2012-2013).
- Analysis of electronic medical records (EMR) for risk factor development (ICD codes) and treatment (2014-2016).
- Comparison of risk factor development and management across racial groups and age.
Main Results:
- Significant increases observed in hypertension (1.7x), hyperlipidemia (4.5x), migraines (2.2x), and diabetes (2x) post-preeclampsia.
- Black non-Hispanics showed the highest rates of hypertension, obesity, and migraines.
- Treatment rates varied, with no hyperlipidemia patients receiving statins; Black non-Hispanics had higher management rates than white Hispanics.
Conclusions:
- Preeclampsia is associated with a marked increase in cerebrovascular risk factors.
- There are opportunities for improved early treatment of these conditions.
- Proactive management can potentially lower the long-term stroke risk for women with a history of preeclampsia.
Objective:
To evaluate the development and management of cerebrovascular risk factors following a pregnancy with preeclampsia.
Methods:
This is a retrospective chart review including women diagnosed with preeclampsia between 2012 and 2013 with later encounters within 2014-2016. For each subject that met inclusion criteria, the development of cerebrovascular risk factors was determined using ICD codes within the 2014-2016 electronic medical record (EMR). For subjects who developed risk factors, current treatment was determined from the EMR. Demographic data was also documented. Differences in the development and treatment of risk factors were compared among racial groups and age. Descriptive statistics were calculated using SAS statistical software.
Results:
Compared to prepregnancy health status, the incidence of hypertension increased by 1.7 times (P < .05), hyperlipidemia increased by 4.5 (P < .05), migraines increased by 2.2 (P < .05), and diabetes mellitus increased by 2 (P < .05) after a pregnancy with preeclampsia. Black non-Hispanics had highest rates of hypertension, obesity, and migraines (20.5%, 9.1%, and 6.8%, respectively.) Of hypertensives, 73.6% (42/57) were prescribed medication. Of diabetics, 88.9% (16/18) were prescribed medication. No patients with hyperlipidemia were prescribed a statin. Black non-Hispanics had higher rates of risk factor management (74.3% of hypertensives and 100% of diabetics treated) than white Hispanics (55% and 77.8%, respectively).
Conclusions:
This study shows a significant increased risk of the development of cerebrovascular risk factors such as hypertension, hyperlipidemia, migraines, and diabetes following a diagnosis of preeclampsia. Opportunities exist for the early treatment of these risk factors, which could reduce the long-term rate of stroke in these women.
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