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Computed tomography (CT) in children with herpes simplex encephalitis.

A Taccone¹, G Gambaro, M Ghiorzi

¹Department of Radiology, Institute G. Gaslini Children's Hospital, Genoa, Italy.

Pediatric Radiology

|January 1, 1988

Summary

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Computed Tomography (CT) scans reveal distinct findings in infants with herpes simplex virus encephalitis (HSE). Early signs include edema and mass effect, differing from adult presentations.

Area of Science:

Neurology
Pediatrics
Radiology

Background:

Herpes simplex virus encephalitis (HSE) is a severe neurological infection.
Understanding imaging findings in pediatric HSE is crucial for diagnosis and management.
Computed Tomography (CT) is a key diagnostic tool.

Purpose of the Study:

To describe the early and follow-up CT findings in infants with HSE.
To compare CT findings in neonates and young children with HSE to those in adults.

Main Methods:

Retrospective analysis of CT scans from nine infants diagnosed with HSE.
Detailed examination of early CT scans and follow-up imaging.

Main Results:

Early CT findings included generalized or localized edema and mass effect in two cases.

Related Experiment Videos

Follow-up CT revealed bilateral gyriform calcification in two patients, a rare finding.

Multicystic encephalomalacia was observed in one patient three months post-onset.

CT findings in infants differed significantly from those typically seen in adult HSE patients.

Conclusions:

Infant HSE presents with unique CT imaging characteristics.
Early detection of edema and mass effect on CT is important.
Follow-up imaging can reveal complications like calcification and encephalomalacia.