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Is bone marrow biopsy a prognostic parameter in B-CLL?
M Raphael1, C Chastang, J L Binet
1Département d'Hématologie, CHU Pitié-Salpêtrière, Paris, France.
Nouvelle Revue Francaise D'Hematologie
|January 1, 1988
Abstract:
Four hundred and ninety-three bone marrow biopsies from CLL patients were analysed on the basis of non diffuse versus diffuse bone marrow lymphocytic infiltration patterns. In each clinical stage A, B, and C there were non significant differences in survival rates according to the bone marrow pattern. However in stage A studying the evolution to stage B or C, a significant difference between patients with non diffuse and diffuse pattern was observed.