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Electric source imaging for presurgical epilepsy evaluation: current status and future prospects
Pierre Mégevand1,2, Margitta Seeck1
1Epilepsy Unit, Neurology Division, Clinical Neuroscience Department, Geneva University Hospitals, Genève, Switzerland.
Expert Review of Medical Devices
|April 1, 2020
Summary
Electric source imaging (ESI) accurately pinpoints epilepsy sources using electroencephalography (EEG). This technique is valuable for presurgical epilepsy management, complementing other diagnostic tools.
Area of Science:
- Neuroscience
- Medical Imaging
Background:
- Electroencephalography (EEG) records brain activity.
- Electric Source Imaging (ESI) estimates cerebral sources of EEG signals.
- Advancements in EEG technology and analysis enable ESI application to epilepsy.
Purpose of the Study:
- To review the use of ESI in epilepsy patients undergoing presurgical evaluation.
- To assess the accuracy and clinical relevance of ESI in epilepsy management.
Main Methods:
- Narrative review of selected original research articles.
- Comparison of ESI accuracy against intracranial EEG and seizure control outcomes.
- Evaluation of ESI's complementary role with MRI and PET.
Main Results:
- ESI accurately localizes epilepsy-related brain activity.
- ESI findings are validated by intracranial EEG and surgical outcomes.
- ESI provides clinically relevant information that complements other imaging modalities.
Conclusions:
- Electric Source Imaging (ESI) is an accurate method for localizing epileptic activity.
- ESI complements existing diagnostic tools in presurgical epilepsy evaluation.
- ESI should be integrated into routine clinical neurophysiology and epilepsy center practices.

