Related Experiment Video
Updated: Dec 25, 2025

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
Published on: June 26, 2013
Single centre versus multi-centre pooled morbidity data in PCNL and the implications for informed consent.
A Auer1, M Barabas2, J Coode-Bate2
1Department of Urology, Portsmouth NHS Trust, Portsmouth, UK.
This study on percutaneous nephrolithotomy (PCNL) outcomes found low complication rates in a single center. Utilizing single-center data is recommended for transparent patient consent regarding PCNL results.
Area of Science:
- Urology
- Nephrology
- Surgical Outcomes
Background:
- Existing national and international outcome data for PCNL may not represent individual hospital or surgeon performance.
- There is a need for single-center data to provide more accurate outcomes for patient consent.
Purpose of the Study:
- To analyze the outcomes of percutaneous nephrolithotomy (PCNL) at a single center.
- To compare single-center PCNL outcomes with existing multi-center data.
- To inform patient consent processes with accurate, localized outcome data.
Main Methods:
- A combination of retrospective and prospective data from 2000-2016 was collated.
- Data from 801 unique PCNL cases were analyzed.
- Outcomes were compared against published large single and multi-center series.
Main Results:
- The mean hemoglobin drop was 1.65 g/dL, with a 3.37% transfusion rate.
- Pre-operative bacteriuria (25%) was noted, but not significantly linked to increased hemoglobin drop.
- Low rates of complications were observed, including 1% requiring higher care, 0.75% needing embolization for bleeding, and no peri-operative deaths.
Conclusions:
- Single-center outcome data for PCNL provides a more accurate reflection of performance.
- Utilizing single-center data is crucial for facilitating transparent patient consent.
- This study demonstrates favorable outcomes and low complication rates in PCNL performed at a single institution.
More Related Videos
06:28E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
04:53A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
Related Concept Videos
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...