[Flecainid intoxication: Evolution, complications and care of]

Area of Science:

• Pharmacology
• Cardiology
• Neurology

Background:

• Flecainide is an antiarrhythmic medication.
• Asperger syndrome is a neurodevelopmental disorder.

Observation:

• A 24-year-old male with Asperger syndrome ingested a significant quantity of flecainide.
• The patient developed ventricular tachycardia, a serious adverse effect.

Findings:

• The ventricular tachycardia was attributed to flecainide's membrane-stabilizing effect.
• Prolonged intensive care unit stay was necessitated by the adverse event.
• Literature review indicated mid-term leaching of flecainide, suggesting delayed toxicity.

Implications:

• This case underscores the importance of considering delayed toxicity from flecainide, particularly in patients with neurodevelopmental disorders.
• Awareness of flecainide leaching is crucial for managing overdose cases.
• Further research into flecainide pharmacokinetics and toxicity in specific patient populations is warranted.