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Updated: Dec 25, 2025

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol
Published on: March 25, 2020
Adsorptive removal of cholesterol by biodegradable zein-graft-β-cyclodextrin film
Xuemeng Jia1, Ning Yang1, Xuchao Qi1
1State Key Laboratory of Separation Membranes and Membrane Processes, National Center for International Joint Research on Separation Membranes, Tiangong University, Tianjin 300387, China.
Abstract:
A novel bio-based zein-graft-β-cyclodextrin film was synthesized for cholesterol adsorption at room temperature. Immobilization of β-cyclodextrin (β-CD) to zein was achieved by the Maillard reaction and the zein-graft-β-CD powders showed higher glass transition temperature and higher solubility in water. Zein-graft-β-CD films, prepared by solvent evaporation casting, showed excellent capacity for cholesterol adsorption. The F1:1 has the best adsorption properties, and the maximum adsorption capacity can reach 5.70 ± 0.56 mg cholesterol/g film. The adsorption cholesterol mechanism of zein-graft-β-CD film was correspond to the pseudo-first order kinetic model. In addition, the zein-graft-β-CD film retained an adsorption capacity of 3.10 ± 0.89 mg cholesterol/g film after three reuses. Using composite enzyme (1 mg/mL papain and 1 mg/mL amylase), the film (F1:1) degradation reached 98.81% in 1 week. These results suggest that zein-graft-β-CD film has potential as a nature-based adsorbent for cholesterol adsorption and could be used in the food industry.
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