Related Experiment Video
Updated: Dec 25, 2025

09:14
Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
Published on: October 18, 2024
844
Successful Lung Transplantation After Acellular Ex Vivo Lung Perfusion With Prone Positioning
Hiromichi Niikawa1, Toshihiro Okamoto2, Kamal S Ayyat1
1Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
The Annals of Thoracic Surgery
|April 1, 2020
Abstract:
Use of prone positioning during ex vivo lung perfusion (EVLP) with the Toronto protocol reduced pulmonary edema in marginal human donor lungs. This report describes 2 cases in which prone positioning during EVLP significantly reduced lung weight. One of the 2 cases resulted in successful double-lung transplantation.

