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Related Experiment Videos

Enzymes as denture cleansers.

E Budtz-Jörgensen, J Kelstrup

    Scandinavian Journal of Dental Research
    |March 1, 1977
    PubMed
    Summary

    Enzymes in dissolvent tablets effectively removed denture plaque and improved oral health in denture stomatitis patients. Mixed enzyme preparations showed superior results compared to single enzymes or commercial cleansers.

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    Area of Science:

    • Biochemistry
    • Oral Medicine
    • Microbiology

    Background:

    • Denture plaque contributes to denture stomatitis.
    • Enzymatic cleaning offers a potential therapeutic approach.

    Purpose of the Study:

    • To evaluate the efficacy of dextranase, mutanase, and protease in dissolvent tablets for removing denture plaque.
    • To assess the impact of these enzymes on clinical parameters of denture stomatitis.

    Main Methods:

    • A double-blind study involving 100 denture wearers with denture stomatitis.
    • Enzymes (dextranase, mutanase, protease) were tested in pure and mixed preparations within dissolvent tablets.
    • Placebo and Steradent were used as controls.
    • Evaluated parameters included denture plaque amount, palatal erythema, and yeast/inflammatory cell concentrations.

    Main Results:

    • Mixed enzyme preparations in dissolvent tablets were significantly more effective than pure enzyme tablets, placebo, or Steradent.
    • A notable reduction in denture plaque was observed.
    • Clinical improvement in palatal mucosa condition was significant.

    Conclusions:

    • Mixed enzyme dissolvent tablets represent a highly effective method for managing denture plaque.
    • These enzymatic preparations offer a beneficial therapeutic option for patients with denture stomatitis.

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