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Related Experiment Videos

Thyroid hormone concentrations in selenium deficient and selenium sufficient cattle.

J R Arthur1, P C Morrice, G J Beckett

  • 1Biochemistry Division, Rowett Research Institute, Bucksburn, Aberdeen.

Research in Veterinary Science
|July 1, 1988
PubMed
Summary

Selenium deficiency in calves alters thyroid hormone levels, increasing thyroxine and decreasing tri-iodothyronine. This selenium deficiency also impacts kidney function and alkaline phosphatase activity.

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Area of Science:

  • Veterinary Medicine
  • Animal Nutrition
  • Biochemistry

Background:

  • Selenium is an essential trace element crucial for various physiological processes.
  • Thyroid hormone metabolism plays a vital role in animal growth and development.
  • Selenium deficiency has been linked to various health issues in livestock.

Purpose of the Study:

  • To investigate the impact of selenium deficiency on thyroid hormone concentrations in calves.
  • To explore the relationship between selenium status and kidney function markers.
  • To understand how selenium deficiency affects alkaline phosphatase activity.

Main Methods:

  • Comparison of selenium-deficient calves with selenium-supplemented calves.
  • Measurement of plasma concentrations of thyroxine and tri-iodothyronine.

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  • Analysis of plasma urea, creatinine, and alkaline phosphatase levels.

    • Main Results:

    • Selenium-deficient calves exhibited higher plasma thyroxine and lower plasma tri-iodothyronine concentrations compared to supplemented calves.
    • Significant increases in plasma urea and creatinine were observed in selenium-deficient calves.
    • Plasma alkaline phosphatase activity was decreased in selenium-deficient calves.

    Conclusions:

    • Low selenium status can disrupt thyroid hormone metabolism in calves.
    • Selenium deficiency may contribute to kidney function abnormalities and altered enzyme activity.
    • These findings provide insights into the physiological effects of selenium deficiency in cattle.