Dispersion correction for optical coherence tomography by the stepped detection algorithm in the fractional Fourier...

Dispersion in optical coherence tomography (OCT) leads to a series of wavelength-dependent phase distortions, which cause degradation of axial resolution. Due to the lack of prior information or the complexity of an exhaustive search calculation, all-depth dispersion suppression can hardly be realized in practical cases, especially for high-speed processing and irregular-structure samples. This paper explores the understanding of the depth-dependent dispersion in the fractional Fourier domain (FRFD) and addresses a new method for dispersion correction based on the FRFD stepped detection algorithm that is able to adaptively compensate the dispersion at all depths of the sample. For the detection of each dispersion component, a coarse search followed by a localized fine search is presented in our algorithm to reduce the calculation complexity with high accuracy guaranteed. A signal separation method utilizing FRFD filtering is also designed to avoid the interference between the dispersion from different depths of the sample, which allows all-depth dispersion correction. The proposed algorithm is verified to be effective through the stratified media of ZnSe. The application of the proposed algorithm in OCT imaging of onion and human coronary artery also demonstrates the feasibility of our algorithm for dispersion correction in bio-tissues.