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COVID-19: what has been learned and to be learned about the novel coronavirus disease

Ye Yi1, Philip N P Lagniton1, Sen Ye1

  • 1Institute of Translational Medicine, and Centre of Reproduction, Development and Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau, China.

International Journal of Biological Sciences
|April 1, 2020
PubMed

Insights

The Coronavirus disease 2019 (COVID-19) outbreak, caused by SARS-CoV-2, is a global health crisis. This review covers COVID-19 epidemiology, virology, and prevention, aiding understanding and eradication efforts.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • The emergence of Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, presents a significant global health threat.
  • COVID-19 shares similarities with SARS-CoV but exhibits higher transmissibility and affects specific demographics, including the elderly, men, and a broader population.
  • The rapid increase in research necessitates a consolidated overview of the evolving understanding of the disease.

Purpose of the Study:

  • To provide a comprehensive review of the current research on COVID-19.
  • To consolidate information on the epidemiology, etiology, virology, diagnosis, treatment, prognosis, and prevention of COVID-19.
  • To aid in the understanding and control of the SARS-CoV-2 pandemic.

Main Methods:

  • Literature review of rapidly developing research on COVID-19.
  • Synthesis of information from various scientific publications.
  • Compilation of data on disease characteristics and management strategies.

Main Results:

  • COVID-19, caused by SARS-CoV-2, has a lower severity and mortality than SARS but is more transmissible.
  • The disease disproportionately affects the elderly and men.
  • A comprehensive overview of key aspects of COVID-19 is presented, highlighting areas needing further investigation.

Conclusions:

  • Despite ongoing research, many questions regarding SARS-CoV-2 remain unanswered.
  • This review aims to enhance the understanding of COVID-19 to support eradication efforts.
  • Continued research and information dissemination are crucial for managing the COVID-19 pandemic.

Keywords:
COVID-19CoronavirusSARS-CoV-2outbreakpneumonia

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