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Published on: June 27, 2025
Primary mesenteric vein thrombosis: a case series
Roberto Marconato1, Giulia Nezi1, Giovanni Capovilla1
1Department of Surgical, Oncological and Gastrointestinal Sciences, University of Padova, Padova, Italy.
Abstract:
Mesenteric vein thrombosis (MVT) is a rare condition, often misdiagnosed due to its vague and misleading clinical presentation. It can cause intestinal infarction, peritonitis, and consequently necessitate bowel resection. CT scanning with intravenous contrast enhancement is the gold standard for its diagnosis. Radiologists have an important role in defining the extent of thrombosis and identifying any signs of intestinal infarction influencing the decision whether or not to operate. In patients with no clinical signs of peritonitis or radiological evidence of intestinal infarction, the treatment can be exclusively medical, based on full anticoagulation (initially with low molecular weight heparin, followed by vitamin K antagonists or direct acting oral-anticoagulants). The duration of medical treatment depends on radiological evidence of resolution of thrombosis and the identification of pro-coagulant risk factors.
Insights
Mesenteric vein thrombosis (MVT) is a rare condition that can lead to serious complications. Early diagnosis via CT scans and appropriate anticoagulation therapy are key to successful management and preventing surgery.
Area of Science:
- Vascular Surgery
- Gastroenterology
- Radiology
Background:
- Mesenteric vein thrombosis (MVT) is an uncommon vascular emergency with often vague symptoms, leading to delayed diagnosis and potential intestinal infarction.
- Accurate diagnosis and assessment of complications like intestinal infarction are critical for surgical decision-making in MVT.
- Current management strategies involve a combination of diagnostic imaging and therapeutic interventions, including anticoagulation.
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