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A Comparison of Four Cardiovascular Risk Assessment Instruments in Saudi Patients
Manar Hasabullah1, Fatamah Kahtani1, Tasneem Balkhoyor1
1Cardiology, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Insights
This study evaluated four cardiovascular disease (CVD) risk calculators in Saudi patients. The ACC/AHA tool best predicted high-risk individuals, while QRISK® showed high applicability for population studies.
Area of Science:
- Cardiology
- Public Health
- Medical Informatics
Background:
- Cardiovascular disease (CVD) risk calculators lack population-specific validation.
- Accurate CVD risk assessment is crucial for preventative strategies.
Purpose of the Study:
- To compare the predictability of four CVD risk assessment instruments in Saudi Arabian patients.
- To identify the most suitable risk calculator for Saudi populations.
Main Methods:
- Investigated Framingham Risk Score (FRS), SCORE, ACC/AHA, and QRISK®.
- Recruited 129 Saudi patients (≥40 years) with acute coronary syndrome.
- Collected data on demographics, clinical factors, and medical history.
Main Results:
- ACC/AHA demonstrated higher predictability for both low (26.3%) and high (66.7%) risk groups.
- QRISK® showed high applicability (95.3%), whereas SCORE had low applicability (22.5%).
Conclusions:
- QRISK® is practical for population-based studies due to its ease of implementation and high applicability.
- ACC/AHA is superior for predicting high-risk individuals within the Saudi population.
Abstract:
Introduction Several cardiovascular risk calculators are available online to measure the probability of developing cardiovascular disease (CVD) without defining the appropriate population. In the current study, four risk assessment instruments were investigated with Saudi Arabian patients with CVD to identify the instrument with the best predictability. The chosen instruments were the Framingham Risk Score (FRS), Systematic Coronary Risk Evaluation (SCORE), American College of Cardiology/American Heart Association (ACC/AHA) Atherosclerotic Cardiovascular Disease Risk Estimator, and the United Kingdom score which is called QRISK®. Methods Saudi patients, 40 years and older, with acute coronary syndrome, were recruited. Data related to age, gender, ethnicity, height, weight, systolic blood pressure, total cholesterol, high-density lipoprotein (HDL), smoking status, diabetes mellitus, rheumatoid arthritis, chronic kidney disease, atrial fibrillation, heart attack in a first-degree relative, and use of antihypertensive treatment were recorded. Results Out of 129 patients, the ACC/AHA had higher predictability with low risk (26.3%) and high risk (66.7%) groups. The QRISK® was highly applicable (95.3%); however, the SCORE was not considered applicable (22.5%). Conclusion The QRISK® is easy to implement and applicable in a population-based study, but the ACC/AHA is superior in predicting individuals with a high risk of CVD.
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