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Clindamycin therapy of cerebral toxoplasmosis in an AIDS patient
1Marshall University School of Medicine, Department of Medicine, Huntington, West Virginia 25755-9410.
Scandinavian Journal of Infectious Diseases
|January 1, 1988
Abstract:
A 47-year-old patient with AIDS and cerebral toxoplasmosis was treated with sulfadiazine pyrimethamine for 5 days. After developing a severe rash his regimen was changed to clindamycin 600 mg q 6 h intravenously and pyrimethamine 25 mg daily, given for 37 days. This resulted in improvement of clinical symptoms and complete resolution of CT scan abnormalities. Clindamycin combined with pyrimethamine may be a useful alternative therapy for cerebral toxoplasmosis in patients who can not tolerate sulfonamides.