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Updated: Dec 25, 2025

Efficient Agroinfiltration of Plants for High-level Transient Expression of Recombinant Proteins

Efficient Agroinfiltration of Plants for High-level Transient Expression of Recombinant Proteins

Published on: July 23, 2013

Recombinant Plant Engineering for Immunotherapeutic Production.

Ankit Singh¹, Gurminder Kaur², Sanchita Singh³

¹1Department of Biosciences, Jamia Millia Islamia University, New Delhi, 110025 India.

Current Molecular Biology Reports

|April 1, 2020

Summary

This summary is machine-generated.

Molecular farming using plants offers a cost-effective method for producing therapeutic proteins. This approach promises accessible, safe, and scalable bio-therapeutics, especially for developing nations.

Keywords:

Immunotherapeutics Molecular farming Plant-based vaccines Plantibodies Supplements and effector molecules Therapeutic proteins

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Area of Science:

Biotechnology
Molecular Farming
Plant-based Bioreactors

Background:

The demand for therapeutic proteins necessitates innovative production methods.
Plant-based bioreactors offer a promising alternative for manufacturing recombinant proteins.

Purpose of the Study:

To review the current status and challenges of molecular farming for producing low-cost bio-therapeutics.
To highlight the potential of plant-based production for developing countries.

Main Methods:

Review of existing literature on plant expression systems for therapeutic protein production.
Analysis of advantages and challenges of molecular farming.

Main Results:

Various plant parts serve as effective expression systems for therapeutic proteins.
Plant-derived therapeutics are free from toxic components and can be produced globally.
Successful commercial products have emerged, with ongoing development of new methods.

Conclusions:

Plants are advantageous bio-factories due to protein synthesis and post-translational modification similarities to animal cells.
Molecular farming offers flexibility, scalability, and low cost with reduced contamination risk.
Further optimization is needed to upscale production for pharmaceutical industry use.