Related Experiment Video
Updated: Dec 25, 2025
08:07
Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
1.3K
A core outcome set for future endometriosis research: an international consensus development study
Summary
A core outcome set for endometriosis was developed to standardize research. This set includes outcomes for pain, infertility, and general treatment satisfaction in clinical trials.
Area of Science:
- Gynecology
- Reproductive Medicine
- Clinical Trial Methodology
Background:
- Endometriosis significantly impacts women's health and quality of life.
- Standardized outcome measures are crucial for evaluating endometriosis treatments effectively.
- Previous research lacked a consensus on essential outcomes for clinical trials.
Purpose of the Study:
- To establish a consensus-driven core outcome set for endometriosis research.
- To standardize the selection, collection, and reporting of outcomes in clinical trials and systematic reviews.
- To improve the comparability and reliability of evidence for endometriosis treatments.
Main Methods:
- A consensus development study involving an international collaboration.
- Utilized a modified Delphi method and a modified nominal group technique.
- Included 116 healthcare professionals, 31 researchers, and 206 patient representatives.
Main Results:
- A core outcome set was defined for pain and symptom management (overall pain, most troublesome symptom, quality of life).
- Specific core outcomes for infertility trials were identified (viable pregnancy, pregnancy loss, live birth, etc.).
- Two universal core outcomes were established: adverse events and patient satisfaction with treatment.
Conclusions:
- A robust core outcome set for endometriosis has been developed through consensus.
- This standardized set will enhance the quality and consistency of future endometriosis research.
- The core outcome set aims to improve treatment evaluation and patient care for endometriosis.
