Related Experiment Video

Updated: Aug 15, 2026

PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRP
06:36

PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRP

Published on: April 9, 2013

[Plasmapheresis in severe forms of suppurative-septic diseases in children]

V G Tsuman, D S Duriagin, E A Semilov

    Vestnik Khirurgii Imeni I. I. Grekova
    |June 1, 1988
    PubMed

    Insights

    Discrete plasmapheresis effectively detoxifies severe pyo-septic diseases in children. This treatment improves hemodynamics, immunity, reduces mortality, and shortens hospital stays, making it a valuable therapeutic option.

    Area of Science:

    • Pediatric critical care medicine
    • Immunology
    • Infectious diseases

    Context:

    • Severe pyo-septic diseases pose significant risks in pediatric patients.
    • Detoxification strategies are crucial for managing critical illness.
    • Limited therapeutic options exist for severe pediatric infections.

    Purpose:

    • To evaluate the efficacy and impact of discrete plasmapheresis in pediatric patients with severe pyo-septic diseases.
    • To describe the application and methodology of discrete plasmapheresis in this cohort.
    • To assess the influence of discrete plasmapheresis on hemodynamic and immunological parameters.

    Summary:

    • Discrete plasmapheresis was applied to 44 children (6 months–14 years) with severe pyo-septic diseases.
    • The procedure demonstrated a positive effect on hemodynamics and key indicators of cell and humoral immunity.
    • Significant improvements included rapid endotoxemia resolution, reduced lethality, and shorter hospitalization periods.

    Impact:

    • Discrete plasmapheresis offers a promising approach for pediatric detoxification in severe infections.
    • The method contributes to improved patient outcomes, including reduced mortality and faster recovery.
    • Wider clinical adoption of discrete plasmapheresis in pediatric pyo-septic disease management is recommended.

    More Related Videos

    Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression07:30

    Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression

    Published on: June 15, 2019

    Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review05:06

    Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review

    Published on: March 27, 2026

    Related Concept Videos

    Asepsis01:28

    Asepsis

    The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
    Chronic Pharyngitis01:23

    Chronic Pharyngitis

    Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
    Etiology
    It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
    Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
    Acute Pyelonephritis II: Diagnostic Studies and Management01:28

    Acute Pyelonephritis II: Diagnostic Studies and Management

    Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
    Streptococcal Pharyngitis01:27

    Streptococcal Pharyngitis

    Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
    Diphtheria01:28

    Diphtheria

    Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
    Brain Abscess l: Introduction01:26

    Brain Abscess l: Introduction

    A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...