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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

263
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
233
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

263
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
263
Kidney Structure01:45

Kidney Structure

74.1K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
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Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol
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Living Kidney Donor Evaluation.

Guillaume Claisse1, François Gaillard2, Christophe Mariat1

  • 1Nephrology, Dialysis and Renal Transplantation Department, Hôpital Nord, CHU de Saint-Etienne, Jean Monnet University, Université de Lyon, Saint-Etienne, France.

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|April 2, 2020
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Summary
This summary is machine-generated.

Long-term living kidney donation (LKD) safety concerns are prompting stricter donor selection criteria. A risk-based approach and improved renal function assessment are crucial for ethical and safe LKD practices.

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Area of Science:

  • Nephrology
  • Transplantation Medicine
  • Medical Ethics

Background:

  • Growing concerns regarding the long-term safety of living kidney donation (LKD), particularly for younger donors, are impacting the transplant community.
  • These concerns necessitate rigorous and adaptable criteria for living donor selection.

Purpose of the Study:

  • To critically review existing LKD guidelines post-2010 for consistency and universality in donor selection thresholds.
  • To introduce the integrative risk-based approach for LKD from the 2017 Kidney Disease: Improving Global Outcomes (KDIGO) guidelines.
  • To discuss issues related to predonation renal function evaluation, specifically glomerular filtration rate (GFR) assessment.

Main Methods:

  • Review and critical analysis of LKD guidelines published after 2010.
  • Examination of the paradigm shift introduced by the 2017 KDIGO guidelines.
  • Discussion of challenges in assessing donor candidate GFR.

Main Results:

  • Existing guidelines (post-2010) show inconsistencies in specific donor acceptance/rejection thresholds.
  • The 2017 KDIGO guidelines advocate for a novel, integrative risk-based approach to LKD.
  • Predonation GFR assessment remains a central, yet complex, criterion in donor selection.

Conclusions:

  • Current LKD guidelines require harmonization to ensure consistent practices.
  • A risk-based approach offers a more nuanced framework for LKD donor selection.
  • Standardized and accurate GFR assessment is vital for safe LKD.