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Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products

Brian Lee1, Breanna S Borys2, Michael S Kallos2

  • 1PBS Biotech, Inc., Camarillo, CA 93012, USA.

Bioengineering (Basel, Switzerland)
|April 2, 2020
PubMed

Keywords:
U-shaped vesselVertical-Wheelallogeneic cell therapycell aggregatecomputational fluid dynamicsdifferentiationexpansionhomogeneous hydrodynamic environmenthuman embryonic stem cellinduced pluripotent stem cellscalable manufacturingscale upshear stresssingle-use bioreactorturbulent energy dissipation rates

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