Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

142
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
142
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

611
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
611
Biopharmaceutics and Pharmacokinetics: Overview01:28

Biopharmaceutics and Pharmacokinetics: Overview

3.1K
Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
3.1K
Dosage Regimen: Individualization01:24

Dosage Regimen: Individualization

120
Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
120
Dosage Regimens: Partial Pharmacokinetic Parameters01:01

Dosage Regimens: Partial Pharmacokinetic Parameters

98
It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
98
Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

209
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
209

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of Potentially Inappropriate Medications for Adults Below 65 Years: Protocol for a Modified Delphi Study.

JMIR research protocols·2026
Same author

Association between initial benzodiazepine prescribing patterns and time to benzodiazepine discontinuation: A population-based retrospective cohort study.

PLoS medicine·2026
Same author

Designing a computerized decision support system for asthma chronic disease management in community pharmacies.

International journal of clinical pharmacy·2026
Same author

Co-developing an inclusive interprofessional health workforce minimum data standard for enhanced planning and decision-making: A Canadian case with international relevance.

Health policy (Amsterdam, Netherlands)·2025
Same author

Exploring perceived barriers, facilitators, and team roles in addressing prescribing cascades in primary care teams: Insights from interprofessional focus groups.

PloS one·2025
Same author

Before the first class: Engaging students early in curriculum design to support program reform.

Medical teacher·2025
Same journal

Tailoring the CFIR to Medication Adherence Interventions: A Delphi and Living Lab Study.

Pharmacy (Basel, Switzerland)·2026
Same journal

Seasonal Influenza Vaccination Uptake, Illness and Economic Burden, and Vaccine Information Exposure Among Young Adults in the San Francisco Bay Area.

Pharmacy (Basel, Switzerland)·2026
Same journal

Impact of an Interdisciplinary Educational Intervention on Healthcare Provider Knowledge and Beliefs Regarding Opioid Harm Reduction in Older Adults: A Pre-Post Survey Study.

Pharmacy (Basel, Switzerland)·2026
Same journal

From Laboratory to Patient Access: A Scoping Review of the Multi-Dimensional Challenges in Drug Repurposing.

Pharmacy (Basel, Switzerland)·2026
Same journal

Kisspeptin as a Precision Biomarker in Personalized Pharmacy: Implications for Individualized Monitoring of Early Pregnancy Viability.

Pharmacy (Basel, Switzerland)·2026
Same journal

Enhancing Discretion and Consistency in Emergency Contraception Counselling: Implementation of a Digital Support Tool in Community Pharmacies.

Pharmacy (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Dec 25, 2025

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.4K

A Continuing Professional Development Program for Pharmacists Implementing Pharmacogenomics into Practice.

Natalie Crown1,2, Beth A Sproule1,3,4, Miles J Luke2

  • 1Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, M5S 3M2, Canada.

Pharmacy (Basel, Switzerland)
|April 2, 2020
PubMed
Summary
This summary is machine-generated.

This continuing professional development (CPD) program enhanced pharmacists' knowledge and readiness in pharmacogenomics. While most participants improved test scores and felt more competent, some faced challenges integrating pharmacogenomics into practice.

Keywords:
continuing educationcontinuing professional developmentpharmacistspharmacogenomicspharmacy

More Related Videos

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
09:10

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

Published on: May 22, 2018

9.9K
Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
06:21

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

Published on: May 10, 2024

1.1K

Related Experiment Videos

Last Updated: Dec 25, 2025

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.4K
A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
09:10

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

Published on: May 22, 2018

9.9K
Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
06:21

Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer

Published on: May 10, 2024

1.1K

Area of Science:

  • Pharmacogenomics
  • Continuing Professional Development
  • Primary Care Pharmacy

Background:

  • Pharmacogenomics offers personalized medicine but requires specialized pharmacist knowledge.
  • Community and primary care pharmacists need training to integrate pharmacogenomics into practice.

Purpose of the Study:

  • To develop and evaluate a continuing professional development (CPD) program on pharmacogenomics for pharmacists.
  • To assess the program's impact on pharmacists' knowledge, attitudes, and implementation of pharmacogenomics.

Main Methods:

  • A multi-component CPD program including online lectures, a workshop, and case studies.
  • Moore's framework was used for assessment, measuring knowledge (tests), attitudes (surveys), and implementation (interviews).

Main Results:

  • 21/26 pharmacists completed the program with high satisfaction and significantly improved test scores.
  • Participants reported increased knowledge, competence, and comfort with pharmacogenomics.
  • 15 pharmacists implemented pharmacogenomics for 117 patients; interviews revealed implementation challenges despite knowledge gains.

Conclusions:

  • The CPD program effectively improved pharmacists' short-term knowledge and readiness for pharmacogenomics.
  • Challenges remain in the practical integration of pharmacogenomics services into primary care settings.