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Dependence of virus adsorption to the cell surface on the input multiplicity of infection
Abstract:
A state of "saturation" of the cell surface ensues when only 5-10% of the cell surface is "covered" by the adsorbed virions. Hence, this state cannot be explained by an "overcrowding effect" caused by the virions attached to the cell surface. A hypothesis of heterogeneity of the cell surface with regard to the virus absorbtion ("the domain hypothesis") is suitable for explanation.