Related Experiment Video
Updated: Dec 25, 2025

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
Published on: May 27, 2018
Influence of Hydration on the Structure and Interactions of Ethaline Deep-Eutectic Solvent: A Spectroscopic and
Payam Kalhor1, Yan-Zhen Zheng2, Hamad Ashraf1
1MOE Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Abstract:
Deep-eutectic solvents (DESs) are regarded as alternative green solvents to ionic liquids. In this work we report the structural properties and hydrogen bonding (H-bonding) interactions of an aqueous DES system. The used DES, ethaline (ETH), is composed of choline chloride and ethylene glycol (EG) in 1 : 2 molar ratio. The investigations were carried out by FTIR spectroscopy combined with quantum chemical calculations. Excess spectroscopy and two-dimensional correlation spectroscopy (2D-COS) were used to explore the data in detail. The results showed that, upon mixing, ETH transforms to EG dimers and trimers and D2 O clusters transform to various ETH-D2 O complexes. Theoretical calculations show that water molecules insert between the anion and cation of ETH, break the strong doubly ionic Cl-… H-OCh+ H-bond, share charges of the ions and form H-bond with them, thus modulate the interaction properties of ETH. This study deepens our molecular-level understanding of the system and would shed light on its applications.
More Related Videos
Related Concept Videos
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
Entropy and Solvation
Aldehydes and Ketones with Water: Hydrate Formation
The formation of hydrates is a reversible reaction. Hydrate formation is influenced by steric and electronic factors accompanying the alkyl substituents on the carbonyl group: The rate of hydrate formation increases with a decrease in the number of alkyl groups attached to the carbonyl carbon. Hence,...
Aqueous Solutions and Heats of Hydration
When ionic compounds dissolve in water, the ions in the solid separate and disperse uniformly throughout the solution because water molecules surround and solvate the ions, reducing the strong electrostatic forces between them. This process...
Acid-Catalyzed Hydration of Alkenes
Solvating Effects

