Related Experiment Video
Updated: Jul 31, 2026

08:28
Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Rigid gas permeable contact lenses in hyperbaric environments
J F Socks1, J F Molinari, J L Rowey
1Alcon Laboratories, Fort Worth, Texas.
American Journal of Optometry and Physiological Optics
|December 1, 1988
Summary
Hard gas permeable contact lenses can form bubbles under the lens during decompression in hyperbaric environments. These bubbles likely originate from the tear layer, not nitrogen off-gassing from eye tissues.
Area of Science:
- Ophthalmology
- Diving Medicine
- Biomaterials Science
Background:
- Hard gas permeable contact lenses are frequently worn by individuals in various environments.
- Hyperbaric environments involve increased ambient pressure, posing unique physiological challenges.
Purpose of the Study:
- To investigate the occurrence and potential origin of bubbles forming under hard gas permeable contact lenses during simulated decompression in a hyperbaric environment.
Main Methods:
- Twenty-four exposures using three different hard gas permeable contact lens materials were conducted in a hyperbaric chamber.
- Simulated dry air dive profiles included depths of 45.72m, 22.86m, and 11.43m with varying durations.
- Visual observation for bubble formation under the lenses was performed at different simulated depths.
Main Results:
- Bubbles were observed forming under all tested hard gas permeable contact lens materials.
- Bubble formation was detected at simulated depths as shallow as 1.98m, even after less stressful exposures.
- The timing and shallow depth of bubble appearance suggest they do not originate from nitrogen off-gassing from eye tissues.
Conclusions:
- The study indicates that bubble formation under hard gas permeable contact lenses is a common occurrence during hyperbaric decompression.
- Evidence suggests these bubbles originate from the tear layer rather than nitrogen diffusion from ocular tissues.
- Further research may be needed to understand the clinical implications of these bubbles for contact lens wearers in hyperbaric conditions.
Related Concept Videos
Physical Principles Governing Gas Exchange
Gas behavior plays a vital role in understanding bodily processes such as external and internal respiration. External respiration involves the diffusion of oxygen into the blood and carbon dioxide out of it in the lungs. In contrast, internal respiration happens in body tissues, where these gases move in opposite directions.
Gas Laws Governing Respiration
The behavior of gases is guided by Dalton's Law of partial pressures and Henry's Law.
Dalton's Law asserts that the total pressure exerted by...
Gas Laws Governing Respiration
The behavior of gases is guided by Dalton's Law of partial pressures and Henry's Law.
Dalton's Law asserts that the total pressure exerted by...
Deep Sea Microbial Ecology
The deep ocean and its underlying sediments represent vast, largely unexplored microbial habitats that extend far beyond the sunlit photic zone. The photic (euphotic) zone typically spans the upper ~100–200 meters of pelagic waters in the open ocean, but its depth varies geographically and seasonally, where sufficient light supports photosynthetic life. Below this lies the deep sea, spanning roughly 1000–6000 meters (bathypelagic to abyssal zones), with deeper hadal trenches extending beyond...

