Endolimax nana and urticaria.

Area of Science:

• Medical Parasitology
• Gastroenterology
• Dermatology

Background:

• Endolimax nana is typically a commensal protozoan residing in the human colon.
• Gastrointestinal and dermatological symptoms can sometimes be linked to parasitic infections.

Observation:

• A case study involving a 34-year-old Italian woman presenting with chronic urticaria, abdominal pain, diarrhea, and weight loss.
• Symptoms emerged after travel to Vietnam and were associated with mild blood eosinophilia.

Findings:

• Multiple coproparasitological examinations confirmed the presence of Endolimax nana cysts.
• Treatment with metronidazole (2 g/day for 10 days, two courses) led to the eradication of E. nana.
• The patient experienced complete resolution of urticaria and gastrointestinal symptoms without antihistamine use.

Implications:

• This case suggests Endolimax nana, while usually asymptomatic, can be an infrequent cause of significant clinical manifestations including urticaria.
• Highlights the importance of considering parasitic infections in patients with unexplained chronic gastrointestinal and dermatological conditions.
• Demonstrates the efficacy of metronidazole in treating E. nana-associated symptoms.