Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

31.7K
Overview
31.7K
Allergic Drug Reactions01:27

Allergic Drug Reactions

1.3K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.3K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

1.6K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
1.6K
Cross-reactivity00:42

Cross-reactivity

32.7K
Overview
32.7K
Hypersensitivities01:30

Hypersensitivities

6.3K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
6.3K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.3K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacokinetics and pharmacodynamics of AQST-109 sublingual film in oral allergy syndrome: A phase 2 study.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same author

Fish-induced food protein-induced enterocolitis syndrome (FPIES) in children: Geography matters and tolerance is more than a challenge date.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same author

Erratum to "World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update - IV - A quality appraisal with the AGREE II instrument" [World Allergy Organ J 15(2) (February 2022) 100613].

The World Allergy Organization journal·2026
Same author

Meaningful outcomes in food allergy immunotherapy: Measuring what counts.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same author

Age-Appropriate Low Dosing for Food Protein-Induced Enterocolitis Syndrome Oral Food Challenges: Proposing a Standardized Approach.

The journal of allergy and clinical immunology. In practice·2026
Same author

Sunflower Seed Allergy: Natural History, Oral Food Challenge Outcomes, and Review of the Literature.

The journal of allergy and clinical immunology. In practice·2026

Related Experiment Video

Updated: Dec 25, 2025

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.2K

Food allergy prevention: current evidence.

Mary Grace Baker1, Anna Nowak-Wegrzyn2,3

  • 1Department of Pediatrics, Division of Pediatric Allergy and Immunology, Elliot and Roslyn Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Current Opinion in Clinical Nutrition and Metabolic Care
|April 3, 2020
PubMed
Summary

Preventing food allergies involves early introduction of allergenic foods and ensuring dietary diversity for infants, especially those with risk factors like atopic dermatitis. Breastfeeding is also recommended.

More Related Videos

Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.7K
Murine Model of Epicutaneously-Induced Immunomodulation
09:06

Murine Model of Epicutaneously-Induced Immunomodulation

Published on: June 24, 2025

364

Related Experiment Videos

Last Updated: Dec 25, 2025

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.2K
Antigenic Liposomes for Generation of Disease-specific Antibodies
10:31

Antigenic Liposomes for Generation of Disease-specific Antibodies

Published on: October 25, 2018

12.7K
Murine Model of Epicutaneously-Induced Immunomodulation
09:06

Murine Model of Epicutaneously-Induced Immunomodulation

Published on: June 24, 2025

364

Area of Science:

  • Immunology
  • Pediatrics
  • Nutrition Science

Background:

  • Atopic dermatitis is a significant risk factor for food allergy development.
  • Impaired skin barrier and inflammation play roles in food allergy pathogenesis.
  • Family history, timing of food introduction, and vitamin D levels are additional risk factors.

Purpose of the Study:

  • To critically review current research on food allergy prevention strategies.
  • To evaluate the effectiveness of various interventions for preventing food allergies.
  • To synthesize evidence regarding risk factors and protective measures.

Main Methods:

  • Systematic review and critical appraisal of relevant scientific literature.
  • Analysis of epidemiological studies and intervention trials.
  • Synthesis of findings on risk factors and preventive measures.

Main Results:

  • Early introduction of allergenic foods (e.g., peanut) reduces food allergy risk in high-risk infants.
  • Dietary diversity throughout pregnancy, breastfeeding, and early childhood is supported by evidence.
  • Interventions targeting skin barrier function have yielded inconsistent results.

Conclusions:

  • Current guidelines recommend breastfeeding and early introduction of allergenic foods for at-risk infants.
  • Dietary diversity, including fruits, vegetables, and vitamin D sources, is crucial for all infants.
  • Further research is needed to clarify the role of skin barrier interventions in food allergy prevention.