Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epitope-imprinted nanogels for high-performance mass-based detection of pathogenic viruses.

Biosensors & bioelectronics·2026
Same author

Hydrogel Microneedle Array-Based Transdermal Dressing System for Multiplexed Assessment and Intelligent Therapy of Chronic Wounds.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

Optical bio/chemical sensors for vitamin B<sub>12</sub> analysis in food and pharmaceuticals: state of the art, challenges, and future outlooks.

Beilstein journal of nanotechnology·2025
Same author

Tyrosine-Capped Pt Nanozyme Functionalized with cDNA: An Innovative Sensor Designed for One-Step Detection of the miRNA-21 Biomarker.

ACS omega·2025
Same author

Sweet cherry stalks to nanocrystalline cellulose: Synthesis, characterization, and stabilization of insect oil/water Pickering emulsions.

Food chemistry·2025
Same author

Atomic-Level Engineering of Synthetic Receptors for Enhanced Virus Detection and Removal.

Advanced healthcare materials·2025

Related Experiment Video

Updated: Dec 25, 2025

Wideband Optical Detector of Ultrasound for Medical Imaging Applications
08:21

Wideband Optical Detector of Ultrasound for Medical Imaging Applications

Published on: May 11, 2014

11.7K

Recent Progress in Optical Sensors for Biomedical Diagnostics.

Muqsit Pirzada1, Zeynep Altintas1

  • 1Institute of Chemistry, Technical University of Berlin, Straße des 17. Juni 124, 10623 Berlin, Germany.

Micromachines
|April 3, 2020
PubMed
Summary

Optical sensors are revolutionizing healthcare biosensing for rapid, ultrasensitive disease diagnosis. This review highlights their potential in early disease prediction and point-of-care testing devices.

Keywords:
bioluminescencebiomedical diagnosticsbiosensorsellipsometryevanescent wavelight addressable potentiometric sensorsoptical sensorsreflectometric interference spectroscopysurface enhanced Raman scatteringsurface plasmon resonance

More Related Videos

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum
09:23

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Published on: December 13, 2017

6.6K
Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies
07:12

Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies

Published on: November 19, 2020

2.4K

Related Experiment Videos

Last Updated: Dec 25, 2025

Wideband Optical Detector of Ultrasound for Medical Imaging Applications
08:21

Wideband Optical Detector of Ultrasound for Medical Imaging Applications

Published on: May 11, 2014

11.7K
Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum
09:23

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Published on: December 13, 2017

6.6K
Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies
07:12

Real-Time Monitoring of Neurocritical Patients with Diffuse Optical Spectroscopies

Published on: November 19, 2020

2.4K

Area of Science:

  • Biomedical Engineering
  • Optoelectronics
  • Biosensing Technologies

Background:

  • Optical sensors are increasingly explored for healthcare biosensing applications.
  • Their versatility in receptor types and detection mechanisms enables integrated sensing platforms.
  • Recent research (since 2016) shows growing interest in rapid, reproducible, and ultrasensitive clinical assays.

Purpose of the Study:

  • To provide an elaborate review of optical sensors in biomedical diagnostics.
  • To cover recent trends and advancements in the field.
  • To highlight the potential of optical sensors for early disease prediction and point-of-care testing.

Main Methods:

  • Review of approximately 250 research articles published since 2016.
  • Analysis of optical sensors based on various principles including SPR, LSPR, evanescent wave fluorescence, and bioluminescence.
  • Examination of sensor capabilities in detecting toxins, proteins, pathogens, disease biomarkers, and whole cells.

Main Results:

  • Optical sensors demonstrate versatility across diverse receptor types and detection mechanisms.
  • These sensors can analyze a wide range of analytes (toxins, proteins, pathogens, biomarkers, cells) in various media (water, buffer, serum, blood, urine).
  • The reviewed technologies facilitate the development of novel synergistic sensing platforms.

Conclusions:

  • Optical sensors offer significant potential for widespread use in early-stage disease prediction.
  • Advancements in optical sensing are paving the way for improved point-of-care testing devices.
  • The integration of different detection mechanisms enhances the capabilities of biosensing platforms.