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Lenalidomide in follicular lymphoma

Christopher R Flowers1, John P Leonard2,3, Nathan H Fowler1

  • 1Department of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX.

Blood
|April 3, 2020
PubMed

Lenalidomide is an immunomodulatory drug approved in the United States for use with rituximab in patients with relapsed/refractory follicular lymphoma. We reviewed data from trials addressing the safety and efficacy of lenalidomide alone and in combination with rituximab as a first-line therapy and as a treatment of patients with relapsed/refractory follicular lymphoma. Lenalidomide-rituximab has been demonstrated to be an effective chemotherapy-free therapy that improves upon single-agent rituximab and may become an alternative to chemoimmunotherapy.

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