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Updated: Dec 25, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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Lenalidomide in follicular lymphoma.

Christopher R Flowers1, John P Leonard2,3, Nathan H Fowler1

  • 1Department of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX.

Blood
|April 3, 2020
PubMed
Summary

Lenalidomide combined with rituximab offers an effective, chemotherapy-free treatment for follicular lymphoma. This combination shows improved efficacy over single-agent rituximab, potentially replacing traditional chemoimmunotherapy.

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